Identification, antioxidant and cytotoxic potentials of casticin in Vitex agnus-castus fruit from different geographical regions of Turkey
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چکیده
منابع مشابه
Three new diterpenoids from the fruit of Vitex agnus-castus.
Three new labdane-type diterpenoids, viteagnusins F, G, and H, were isolated from the hexane extract of fruit (chasteberry) of Vitex agnus-castus L. (Verbenaceae) along with seven known compounds including four labdane-type diterpenoids, one norlabdane-type diterpenoid, one aromadendrane-type sesquiterpenoid, and one flavonoid. The chemical structures of the three new labdane-type diterpenoids ...
متن کاملVitex agnus-castus
Vitex agnus-castus has a long tradition as a herbal remedy and was used in ancient times not only as an anaphrodisiac and for preserving chastity but also against diverse disturbances of the female genital system. In actual clinical trials, the fruit Agni casti fructus was shown to relieve premenstrual syndrome (PMS) and especially breast swelling and pain, due to its dopaminergic effect. Altho...
متن کاملCytotoxicity of Vitex agnus-castus fruit extract and its major component, casticin, correlates with differentiation status in leukemia cell lines.
We have demonstrated that an extract from the ripe fruit of Vitex agnus-castus (Vitex) exhibits cytotoxic activities against various types of solid tumor cells, whereas its effects on leukemia cells has not been evaluated to date. In this study, the effects of Vitex and its major component, casticin, on leukemia cell lines, HL-60 and U-937, were investigated by focusing on proliferation, induct...
متن کاملAntioxidant activity of different extracts of Vitex agnus-castus (L.) and phytochemical profile
The main goal of this study was to evaluate antioxidant activity of Vitex agnus-castus aerial parts and also to investigate the main phytoconstituents in the plant extracts. Nhexane, dichloromethane, ethyl acetate and methanol 80% extract were tested for free radical scavenging activity on model reaction with stable 2,2-diphenyl-1-picrylhydrazyl radical (DPPH). The results showed that ethyl ace...
متن کاملAlecrim de Angola - Vitex Agnus-castus
Vitex agnus-castus L. (chaste-berry). Phytomedicine. 2004 Jan;11(1):18-23. Liu J, Burdette JE, Sun Y, Deng S, Schlecht SM, Zheng W, Nikolic D, Mahady G, van Breemen RB, Fong HH, Pezzuto JM, Bolton JL, Farnsworth NR. Department of Medicinal Chemistry and Pharmacognosy, UIC/NIH Center for Botanical Dietary Supplements Research, College of Pharmacy, University of Illinois at Chicago, Chicago, Illi...
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ژورنال
عنوان ژورنال: Tropical Journal of Pharmaceutical Research
سال: 2020
ISSN: 1596-9827,1596-5996
DOI: 10.4314/tjpr.v19i6.24